Article
Moderating the Heritability of Body Mass Index by Age and Sex With Genomic Data.
Genetic epidemiology - 1 Feb 2026
Benstock Sarah E, Prom-Wormley Elizabeth, Verhulst Brad
Abstract excerpt
Environmental contexts may increase or decrease the heritability of a phenotype. Or equivalently, people with some genotypes may be more (or less) sensitive to environmental differences. Such genetic sensitivity to environmental contexts is called gene-environment interaction (G × E). While G × E has been robustly detected in twin and model organism studies for numerous phenotypes, there is a lingering perception...
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