Article
Gfi1 Loss Protects against Two Models of Induced Diabetes.
Cells - 20 Oct 2021
Napolitano Tiziana, Avolio Fabio, Silvano Serena, Forcisi Sara, Pfeifer Anja, Vieira Andhira, Navarro-Sanz Sergi, Friano Marika Elsa, Ayachi Chaïma, Garrido-Utrilla Anna, Atlija Josipa, Hadzic Biljana, Becam Jérôme, Sousa-De-Veiga Anette, Plaisant Magali Dodille, Balaji Shruti, Pisani Didier F, Mondin Magali, Schmitt-Kopplin Philippe, Amri Ez-Zoubir, Collombat Patrick
Abstract excerpt
Background: Although several approaches have revealed much about individual factors that regulate pancreatic development, we have yet to fully understand their complicated interplay during pancreas morphogenesis. Gfi1 is transcription factor specifically expressed in pancreatic acinar cells, whose role in pancreas cells fate identity and specification is still elusive. Methods: In order to gain further insight...
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