Article
A generic hidden Markov model for multiparent populations.
G3 (Bethesda, Md.) - 4 Feb 2022
Broman Karl W
Abstract excerpt
A common step in the analysis of multiparent populations (MPPs) is genotype reconstruction: identifying the founder origin of haplotypes from dense marker data. This process often makes use of a probability model for the pattern of founder alleles along chromosomes, including the relative frequency of founder alleles and the probability of exchanges among them, which depend on a model for meiotic recombination...
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