A general approach for haplotype phasing across the full spectrum of relatedness.

doi:10.1371/journal.pgen.1004234

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Article

A general approach for haplotype phasing across the full spectrum of relatedness.

PLoS genetics - 1 Apr 2014

O'Connell Jared, Gurdasani Deepti, Delaneau Olivier, Pirastu Nicola, Ulivi Sheila, Cocca Massimiliano, Traglia Michela, Huang Jie, Huffman Jennifer E, Rudan Igor, McQuillan Ruth, Fraser Ross M, Campbell Harry, Polasek Ozren, Asiki Gershim, Ekoru Kenneth, Hayward Caroline, Wright Alan F, Vitart Veronique, Navarro Pau, Zagury Jean-Francois, Wilson James F, Toniolo Daniela, Gasparini Paolo, Soranzo Nicole, Sandhu Manjinder S, Marchini Jonathan

Abstract excerpt

Many existing cohorts contain a range of relatedness between genotyped individuals, either by design or by chance. Haplotype estimation in such cohorts is a central step in many downstream analyses. Using genotypes from six cohorts from isolated populations and two cohorts from non-isolated populations, we have investigated the performance of different phasing methods designed for nominally 'unrelated'...

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PMID: 24743097
DOI: 10.1371/journal.pgen.1004234
PMCID: PMC3990520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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