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Article

Inbreeding coefficient estimation with dense SNP data: comparison of strategies and application to HapMap III.

Human heredity - 1 Jan 2014

Gazal Steven, Sahbatou Mourad, Perdry Hervé, Letort Sébastien, Génin Emmanuelle, Leutenegger Anne-Louise

Abstract excerpt

BACKGROUND/AIMS: If the parents of an individual are related, it is possible for the individual to have received at 1 locus 2 identical-by-descent alleles that are copies of a single allele carried by the parents' common ancestor. The inbreeding coefficient measures the probability of this event and increases with increasing relatedness between the parents. It is traditionally computed from the observed...

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PMID: 25060269
DOI: 10.1159/000358224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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