Article
Efficient genome ancestry inference in complex pedigrees with inbreeding.
Bioinformatics (Oxford, England) - 15 Jun 2010
Liu Eric Yi, Zhang Qi, McMillan Leonard, de Villena Fernando Pardo-Manuel, Wang Wei
Abstract excerpt
MOTIVATION: High-density SNP data of model animal resources provides opportunities for fine-resolution genetic variation studies. These genetic resources are generated through a variety of breeding schemes that involve multiple generations of matings derived from a set of founder animals. In this article, we investigate the problem of inferring the most probable ancestry of resulting genotypes, given a set of...
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