Article
Accurate Genotype Imputation in Multiparental Populations from Low-Coverage Sequence.
Genetics - 1 Sept 2018
Zheng Chaozhi, Boer Martin P, van Eeuwijk Fred A
Abstract excerpt
Many different types of multiparental populations have recently been produced to increase genetic diversity and resolution in QTL mapping. Low-coverage, genotyping-by-sequencing (GBS) technology has become a cost-effective tool in these populations, despite large amounts of missing data in offspring and founders. In this work, we present a general statistical framework for genotype imputation in such experimental...
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