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Article

Unlocking the Role of Exercise on CD4+ T Cell Plasticity.

Frontiers in immunology - 1 Jan 2021

Goldsmith Chloé D, Donovan Thomasina, Vlahovich Nicole, Pyne David B

Abstract excerpt

A hallmark of T cell ageing is a loss of effector plasticity. Exercise delays T cell ageing, yet the mechanisms driving the effects of exercise on T cell biology are not well elucidated. T cell plasticity is closely linked with metabolism, and consequently sensitive to metabolic changes induced by exercise. Mitochondrial function is essential for providing the intermediate metabolites necessary to generate and...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34759918
DOI: 10.3389/fimmu.2021.729366
PMCID: PMC8573256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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