Article
Cell metabolism: Functional and phenotypic single cell approaches.
Methods in cell biology - 1 Jan 2024
De Biasi Sara, Gigan Julien Paul, Borella Rebecca, Santacroce Elena, Lo Tartaro Domenico, Neroni Anita, Paschalidis Nikolaos, Piwocka Katarzyna, Argüello Rafael José, Gibellini Lara, Cossarizza Andrea
Abstract excerpt
Several metabolic pathways are essential for the physiological regulation of immune cells, but their dysregulation can cause immune dysfunction. Hypermetabolic and hypometabolic states represent deviations in the magnitude and flexibility of effector cells in different contexts, for example in autoimmunity, infections or cancer. To study immunometabolism, most methods focus on bulk populations and rely on in...
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