Article
ALKBH1 gene polymorphisms confer hepatoblastoma susceptibility in Chinese children.
Scientific reports - 21 Jan 2026
He Chongwei, Pan Lingling, Zeng Xinhao, Wang Hua, Yang Zhonghua, Zhang Jiao, Li Yong, Li Li, Li Suhong, Cheng Jiwen, Song Yalan, He Jing, Chen Chaoyang
Abstract excerpt
Hepatoblastoma is the most common malignant liver tumor of embryonic origin in children; however, its underlying etiology remains unclear. N1-methyladenosine (m1A) modification is widely found in various human tissues and has been demonstrated to regulate tumorigenesis, but no studies have explored the role of ALKBH1 in the development of hepatoblastoma. We genotyped three ALKBH1 gene polymorphisms (rs1048147...
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