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Article

Investigations into SCAMP5, a candidate lupus risk gene expressed in plasmacytoid dendritic cells.

Lupus science & medicine - 1 Nov 2021

Ghanem Mustafa H, Shih Andrew J, Vashistha Himanshu, Coke Latanya N, Li Wentian, Kim Sun Jung, Simpfendorfer Kim R, Gregersen Peter K

Abstract excerpt

OBJECTIVE: We have investigated the molecular function of SCAMP5, a candidate risk gene for SLE exclusively expressed in plasmacytoid dendritic cells (pDCs) among peripheral leucocytes. METHODS: We tested the independence of the association in SCAMP5 with SLE by performing conditional analyses. We profiled the expression pattern of SCAMP5 among circulating leucocytes at the transcript and protein levels. Using...

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Identifiers

PMID: 34728555
DOI: 10.1136/lupus-2021-000567
PMCID: PMC8565557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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