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Molecular Characterization of Circulating Plasma Cells in Patients with Active Systemic Lupus Erythematosus

21 Sept 2012

Abstract excerpt

Systemic lupus erythematosus (SLE) is a generalized autoimmune disease characterized by abnormal B cell activation and the occurrence of increased frequencies of circulating plasma cells (PC). The molecular characteristics and nature of circulating PC and B cells in SLE have not been completely characterized. Microarray analysis of gene expression was used to characterize circulating PC in subjects with active...

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PMID: 23028528
DOI: 10.1371/journal.pone.0044362

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