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Article

NUAK Kinases: Brain-Ovary Axis.

Cells - 15 Oct 2021

Molina Ester, Hong Linda, Chefetz Ilana

Abstract excerpt

Liver kinase B (LKB1) and adenosine monophosphate (AMP)-activated protein kinase (AMPK) are two major kinases that regulate cellular metabolism by acting as adenosine triphosphate (ATP) sensors. During starvation conditions, LKB1 and AMPK activate different downstream pathways to increase ATP production, while decreasing ATP consumption, which abrogates cellular proliferation and cell death. Initially, LKB1 was...

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Identifiers

PMID: 34685740
DOI: 10.3390/cells10102760
PMCID: PMC8535158

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