Article
Significant Association of CCND1 Genotypes With Susceptibility to Childhood Acute Lymphoblastic Leukemia.
Anticancer research - 1 Oct 2021
Hsu Pei-Chen, Pei Jen-Sheng, Chen Chao-Chun, Chang Wen-Shin, Chin Yu-Ting, Huang Tai-Lin, Yang Jai-Sing, Wang Yun-Chi, Chen Jaw-Chyun, Hsu Yuan-Nian, Tsai Chia-Wen, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: This study investigated whether genetic variations in cyclin D1 (CCND1) are associated with susceptibility to childhood acute lymphoblastic leukemia (ALL). MATERIALS AND METHODS: A total of 266 childhood ALL cases and 266 healthy controls were genotyped for CCND1 rs9344 and rs678653. RESULTS: There was a significant difference in the genotypic distribution of rs9344 between childhood ALL patients...
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