Article
Frequency of polymorphisms in the IKZF1 and CDKN2A/2B genes and descriptive analysis in pediatric patients with acute lymphoblastic leukemia: a multicenter hospital-based prevalence study in Rio De Janeiro.
BMC cancer - 10 Oct 2024
da Rocha Figueiredo Ariadne, da Conceição Barbosa Thayana, Emerenciano Mariana, Land Marcelo Gerardin Poirot
Abstract excerpt
BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and B-cell ALL (B-ALL) is the most common subtype. The understanding of ALL has advanced significantly in recent years due to genomic sequencing, which has made it possible to identify genetic variants and detect the association between "single nucleotide polymorphisms" (SNP) and certain diseases. METHODS: We evaluated 126...
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