Article
Contribution of Cyclin Dependent Kinase Inhibitor 1A Genotypes to Childhood Acute Lymphocytic Leukemia Risk in Taiwan.
Cancer genomics & proteomics - 1 Jan 2000
Chen Chao-Chun, Tsai Chung-Lin, Pei Jen-Sheng, Tzeng Huey-En, Hsu Pei-Chen, Cheng DA-Chuan, Lin Jiunn-Cherng, Tsai Chia-Wen, Bau DA-Tian, Chang Wen-Shin
Abstract excerpt
BACKGROUND/AIM: The disruption of cell-cycle control can lead to an imbalance in cell proliferation, often accompanied by genomic instability, which in turn can facilitate carcinogenesis. This study aimed to examine the impact of CDKN1A rs1801270 and rs1059234 polymorphisms on the risk of childhood acute lymphocytic leukemia (ALL) in Taiwan. MATERIALS AND METHODS: The genotypes of CDKN1A rs1801270 and rs1059234...
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