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Article

Association of the independent polymorphisms in CDKN2A with susceptibility of acute lymphoblastic leukemia.

Bioscience reports - 29 Jun 2018

Zhou Xueyan, Liao Fei, Zhang Junlong, Qin Yun, Xu Heng, Ding Zhenyu, Zhang Yan, Zhang Feng

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is the most common cancer in children, and alterations in CDKN2A were considered to play an important role on leukemogenesis. Two single nucleotide polymorphisms (SNPs) at CDKN2A locus were identified to impact on ALL susceptibility via genome wide association studies, and followed by multiple subsequent replication studies at the specific hits. Here, we conducted a systematic...

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PMID: 29654170
DOI: 10.1042/BSR20180331
PMCID: PMC6019384

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