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Article

Contribution of Cyclin-dependent Kinase Inhibitor 1B Genotypes to Childhood Leukemia Risk.

In vivo (Athens, Greece) - 1 Jan 2000

Pei Jen-Sheng, Chang Wen-Shin, Hsu Pei-Chen, Chen Chao-Chun, Yang Ya-Chen, Hsu Shih-Wei, Hsu Yuan-Nian, Wang Yun-Chi, Wang Chung-Hsing, Tsai Chia-Wen, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: Although genetic differences in cell-cycle control genes have been associated with cancer risk, to our knowledge, no report has specifically examined the role of gene variants in childhood acute lymphoblastic leukemia (ALL). Cyclin-dependent kinase inhibitor 1B (CDKN1B; also known as p27/KIP1) is a cell-cycle regulating gene. This study aimed at investigating the association between CDKN1B...

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Identifiers

PMID: 35738638
DOI: 10.21873/invivo.12874
PMCID: PMC9301415

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