Cyclin D2 gene variance and expression level in pediatric acute lymphoblastic leukemia.

doi:10.1002/pbc.30678

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Cyclin D2 gene variance and expression level in pediatric acute lymphoblastic leukemia.

Pediatric blood & cancer - 1 Dec 2023

Elwafa Reham Abdel Haleem Abo, Bordiny Magdy El, Salama Mostafa, Fawzy Amira, Omar Omneya Magdy

Abstract excerpt

BACKGROUND: Cyclin D2 (CCND2) is a crucial player in cell cycle regulation. CCND2 polymorphisms contribute to cancer predisposition. OBJECTIVES: To evaluate the association of CCND2 rs3217927 single nucleotide polymorphisms (SNP) and its expression levels with acute lymphoblastic leukemia (ALL) susceptibility in Egyptian children and its potential prognostic role. METHODS: The 5' nuclease allelic discrimination...

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PMID: 37731174
DOI: 10.1002/pbc.30678

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CCND2

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