Plasmodium falciparum AMA1 and CSP antigen diversity in parasite isolates from southern Ghana.

doi:10.3389/fcimb.2024.1375249

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Plasmodium falciparum AMA1 and CSP antigen diversity in parasite isolates from southern Ghana.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Kusi Kwadwo A, Amoah Linda E, Acquah Festus Kojo, Ennuson Nana Aba, Frempong Abena F, Ofori Ebenezer A, Akyea-Mensah Kwadwo, Kyei-Baafour Eric, Osei Frank, Frimpong Augustina, Singh Susheel K, Theisen Michael, Remarque Edmond J, Faber Bart W, Belmonte Maria, Ganeshan Harini, Huang Jun, Villasante Eileen, Sedegah Martha

Abstract excerpt

Introduction: Diversity in malarial antigens is an immune evasion mechanism that gives malaria parasites an edge over the host. Immune responses against one variant of a polymorphic antigen are usually not fully effective against other variants due to altered epitopes. This study aimed to evaluate diversity in the Plasmodium falciparum antigens apical membrane antigen 1 (PfAMA1) and circumsporozoite protein...

Topics

Plasmodium falciparum
Antigens, Protozoan
Ghana
Humans
Protozoan Proteins
Malaria, Falciparum
Membrane Proteins
Antibodies, Protozoan
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Adult

Male

Adolescent

Young Adult

Child

Genetic Variation

Child, Preschool

Middle Aged

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 38808064
DOI: 10.3389/fcimb.2024.1375249
PMCID: PMC11132687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-38808064-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmodium falciparum AMA1 and CSP antigen diversity in parasite isolates from southern Ghana.PMID 38808064Read ↗

Within-population genetic diversity of Plasmodium falciparum vaccine candidate antigens reveals geographic distance from a Central sub-Saharan African origin.Semantic proximity Read ↗

Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decade.Semantic proximity Read ↗

Population genetic analysis of the Plasmodium falciparum circumsporozoite protein in two distinct ecological regions in Ghana.Semantic proximity Read ↗

Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines.Semantic proximity Read ↗

Genetic variations of Plasmodium falciparum circumsporozoite protein and the impact on interactions with human immunoproteins and malaria vaccine efficacy.Semantic proximity Read ↗

Population Genetic Analysis of Plasmodium falciparum Circumsporozoite Protein in Two Distinct Ecological Regions in GhanaSemantic proximity Read ↗

Genetic Diversity of Plasmodium falciparum (Pf) Field Isolates for the Development of Novel Controlled Human Malaria Infection (CHMI) Challenge StrainsSemantic proximity Read ↗

Extreme Genetic Diversity and Signatures of Balancing Selection in Plasmodium vivax Blood-Stage Antigens.Semantic proximity Read ↗

Seasonal variations in Plasmodium falciparum genetic diversity and multiplicity of infection in asymptomatic children living in southern Ghana.Semantic proximity Read ↗

Genetic diversity and natural selection of apical membrane antigen-1 (ama-1) in Cameroonian Plasmodium falciparum isolates.Semantic proximity Read ↗

Allelic diversity and antibody recognition of Plasmodium falciparum merozoite surface protein 1 during hypoendemic malaria transmission in the Brazilian amazon region.Semantic proximity Read ↗

Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.