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Article

Genetic diversity and natural selection of apical membrane antigen-1 (ama-1) in Cameroonian Plasmodium falciparum isolates.

Gene - 5 Feb 2024

Hawadak Joseph, Kojom Foko Loick Pradel, Dongang Nana Rodrigue Roman, Yadav Karmveer, Pande Veena, Das Aparup, Singh Vineeta

Abstract excerpt

Antigenic variation associated with genetic diversity in global Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a major impediment to designing an effective malaria vaccine. Here, we report the first study on genetic diversity and natural selection of the Pfama-1 gene in P. falciparum isolates from Cameroon. A total of 328 P. falciparum positive samples collected during 2016 and 2019 from five...

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Identifiers

PMID: 37925116
DOI: 10.1016/j.gene.2023.147956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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