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Article

Measurement of the plasma levels of antibodies against the polymorphic vaccine candidate apical membrane antigen 1 in a malaria-exposed population.

BMC infectious diseases - 2 Feb 2012

Kusi Kwadwo A, Dodoo Daniel, Bosomprah Samuel, van der Eijk Marjolein, Faber Bart W, Kocken Clemens H M, Remarque Edmond J

Abstract excerpt

BACKGROUND: Establishing antibody correlates of protection against malaria in human field studies and clinical trials requires, amongst others, an accurate estimation of antibody levels. For polymorphic antigens such as apical membrane antigen 1 (AMA1), this may be confounded by the occurrence of a large number of allelic variants in nature. METHODS: To test this hypothesis, plasma antibody levels in an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22299616
DOI: 10.1186/1471-2334-12-32
PMCID: PMC3317819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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