Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C.

PLoS computational biology - 1 Sept 2021

Posada-Céspedes Susana, Van Zyl Gert, Montazeri Hesam, Kuipers Jack, Rhee Soo-Yon, Kouyos Roger, Günthard Huldrych F, Beerenwinkel Niko

Abstract excerpt

Although combination antiretroviral therapies seem to be effective at controlling HIV-1 infections regardless of the viral subtype, there is increasing evidence for subtype-specific drug resistance mutations. The order and rates at which resistance mutations accumulate in different subtypes also remain poorly understood. Most of this knowledge is derived from studies of subtype B genotypes, despite not being the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to HIV Infections

Share to HIV Protease Inhibitors

Share to Lopinavir

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 34491984
DOI: 10.1371/journal.pcbi.1008363
PMCID: PMC8448360

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C.PMID 34491984Read ↗

Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus CSemantic proximity Read ↗

Global Comparison of Drug Resistance Mutations After First-Line Antiretroviral Therapy Across Human Immunodeficiency Virus-1 SubtypesSemantic proximity Read ↗

Discovering human immunodeficiency virus mutational pathways using temporal Bayesian networks.Semantic proximity Read ↗

Forecasting drug resistant HIV protease evolutionSemantic proximity Read ↗

Phylogenetic Network Analyses Reveal the Influence of Transmission Clustering on the Spread of HIV Drug Resistance in Quebec from 2002 to 2022.Semantic proximity Read ↗

A phylogenetic and Markov model approach for the reconstruction of mutational pathways of drug resistance.Semantic proximity Read ↗

Transmission networks of drug resistance acquired in primary/early stage HIV infection.Semantic proximity Read ↗

Bayesian network analysis of resistance pathways against HIV-1 protease inhibitors.Semantic proximity Read ↗

Large-scale inference of conjunctive Bayesian networks.Semantic proximity Read ↗

HIV-1 subtype B protease and reverse transcriptase amino acid covariation.Semantic proximity Read ↗

Forecasting drug resistant HIV protease evolution.Semantic proximity Read ↗

A Bayesian network approach to study host and viral genetic correlates of HIV-1 disease progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.