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Article

Large-scale inference of conjunctive Bayesian networks.

Bioinformatics (Oxford, England) - 1 Sept 2016

Montazeri Hesam, Kuipers Jack, Kouyos Roger, Böni Jürg, Yerly Sabine, Klimkait Thomas, Aubert Vincent, Günthard Huldrych F, Beerenwinkel Niko

Abstract excerpt

UNLABELLED: The continuous time conjunctive Bayesian network (CT-CBN) is a graphical model for analyzing the waiting time process of the accumulation of genetic changes (mutations). CT-CBN models have been successfully used in several biological applications such as HIV drug resistance development and genetic progression of cancer. However, current approaches for parameter estimation and network structure...

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PMID: 27587695
DOI: 10.1093/bioinformatics/btw459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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