Article
Transmission networks of drug resistance acquired in primary/early stage HIV infection.
AIDS (London, England) - 30 Nov 2008
Brenner Bluma G, Roger Michel, Moisi Daniela D, Oliveira Maureen, Hardy Isabelle, Turgel Reuven, Charest Hugues, Routy Jean-Pierre, Wainberg Mark A
Abstract excerpt
OBJECTIVES: Population-based sequencing of primary/recent HIV infections (PHIs) can provide a framework for understanding transmission dynamics of local epidemics. In Quebec, half of PHIs represent clustered transmission events. This study ascertained the cumulative implications of clustering on onward transmission of drug resistance. METHODS: HIV-1 pol sequence datasets were available for all genotyped PHI (<6...
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