Article
Discovering human immunodeficiency virus mutational pathways using temporal Bayesian networks.
Artificial intelligence in medicine - 1 Mar 2013
Hernandez-Leal Pablo, Rios-Flores Alma, Avila-Rios Santiago, Reyes-Terán Gustavo, Gonzalez Jesus A, Fiedler-Cameras Lindsey, Orihuela-Espina Felipe, Morales Eduardo F, Sucar L Enrique
Abstract excerpt
OBJECTIVE: The human immunodeficiency virus (HIV) is one of the fastest evolving organisms in the planet. Its remarkable variation capability makes HIV able to escape from multiple evolutionary forces naturally or artificially acting on it, through the development and selection of adaptive mutations. Although most drug resistance mutations have been well identified, the dynamics and temporal patterns of...
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