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Article

Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction.

International immunopharmacology - 1 Nov 2021

Zeng Zhen, Sun Qing-Qing, Zhang Wei, Wen Qin-Wen, Wang Ting-Hui, Qin Wen, Xiao Dong-Mei, Zhang Zhen, Huang Hua, Mo Yi-Jun, Wu Xiu-Di, Cen Han

Abstract excerpt

OBJECTIVE: This study was performed to replicate the associations of genetic polymorphisms within nuclear factor-κB (NF-κB) signaling pathway genes with rheumatoid arthritis (RA), and to further examine genetic interactions in a Chinese population. METHODS: A total of eleven single-nucleotide polymorphisms (SNPs) were genotyped in 594 RA patients and 604 healthy controls. RESULTS: Genetic association analysis...

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Identifiers

PMID: 34464884
DOI: 10.1016/j.intimp.2021.108089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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