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Article

Genetic interaction between genes involved in NF-κB signaling pathway in systemic lupus erythematosus.

Molecular immunology - 1 Dec 2013

Cen Han, Zhou Mo, Leng Rui-Xue, Wang Wei, Feng Chen-Chen, Li Bao-Zhu, Zhu Yan, Yang Xiao-Ke, Yang Mei, Zhai Yu, Zhang Min, Hu Lin-Feng, Li Rui, Chen Gui-Mei, Chen Hong, Pan Hai-Feng, Li Xiang-Pei, Ye Dong-Qing

Abstract excerpt

Recently, multiple genetic associations have been found between genes involved in nuclear factor-kappaB (NF-κB) signaling pathway and systemic lupus erythematosus (SLE) or other autoimmune diseases. This study was undertaken to replicate some of these associations and further test for genetic interactions among these genes in SLE in a Chinese population. Ten single-nucleotide polymorphisms (SNPs) in NFKB1, REL,...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23911423
DOI: 10.1016/j.molimm.2013.07.006

Genes

NFKB1
TNFAIP3
TNIP1
IKBKB
REL
TRAF6

Provenance

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