Article
Integrative analysis of genome-wide association studies and gene expression analysis identifies pathways associated with rheumatoid arthritis.
Oncotarget - 23 Feb 2016
Zhang Mingming, Mu Hongbo, Lv Hongchao, Duan Lian, Shang Zhenwei, Li Jin, Jiang Yongshuai, Zhang Ruijie
Abstract excerpt
Rheumatoid arthritis (RA) is a complex and systematic autoimmune disease, which is usually influenced by both genetic and environmental factors. Pathway analyses based on a single data type such as microarray data or SNP data have successfully revealed some biology pathways associated with RA. However, we found that the pathway analysis based on a single data type only provide limited understanding about the...
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