Article
Integrative analyses for functional mechanisms underlying associations for rheumatoid arthritis.
The Journal of rheumatology - 1 Jul 2013
Deng Fei-Yan, Lei Shu-Feng, Zhu Hong, Zhang Yong-Hong, Zhang Zeng-Li
Abstract excerpt
OBJECTIVE: Extensive association analyses including genome-wide association studies (GWAS) and powerful metaanalysis studies have identified a long list of loci associated with rheumatoid arthritis (RA) in very large populations, but most of them established statistical associations of genetic markers and RA only at the DNA level, without supporting evidence of functional relevance. Our study serves as a trial to...
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