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Uptake of bilateral-risk-reducing-mastectomy: Prospective analysis of 7195 women at high-risk of breast cancer.

Breast (Edinburgh, Scotland) - 1 Dec 2021

Evans D Gareth, Gandhi Ashu, Wisely Julie, Clancy Tara, Woodward Emma R, Harvey James, Highton Lyndsey, Murphy John, Barr Lester, Howell Sacha J, Lalloo Fiona, Harkness Elaine F, Howell Anthony

Abstract excerpt

BACKGROUND: Bilateral-Risk-Reducing-Mastectomy-(BRRM) is well described in BRCA1/2 pathogenic variant carriers. However, little is known about the relative uptake, time trends or factors influencing uptake in those at increased breast cancer risk not known to be carriers. The aim of this study is to assess these factors in both groups. METHODS: BRRM uptake was assessed from entry to the Manchester Family History...

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Identifiers

PMID: 34464846
DOI: 10.1016/j.breast.2021.08.015
PMCID: PMC8406355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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