Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bilateral risk-reduction mastectomy in BRCA1 and BRCA2 mutation carriers: a meta-analysis.

Annals of surgical oncology - 1 Sept 2015

De Felice Francesca, Marchetti Claudia, Musella Angela, Palaia Innocenza, Perniola Giorgia, Musio Daniela, Muzii Ludovico, Tombolini Vincenzo, Benedetti Panici Pierluigi

Abstract excerpt

BACKGROUND: Women with BRCA1 and BRCA2 mutations have substantially elevated risk of developing breast cancer. The aim of this study was to clarify the role of bilateral risk-reducing mastectomy (BRRM) in reducing breast cancer risk in women carriers of BRCA1 and BRCA2 mutations. METHODS: The Pubmed, MEDLINE and Scopus databases were searched to retrieve articles written in the English language. Two investigators...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Heterozygote

Share to Mastectomy

Share to Mutation

Share to Prognosis

Share to Risk Reduction Behavior

Source

Identifiers

PMID: 25808098
DOI: 10.1245/s10434-015-4532-1

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bilateral risk-reduction mastectomy in BRCA1 and BRCA2 mutation carriers: a meta-analysis.PMID 25808098Read ↗

Does bilateral mastectomy affect clinical outcomes in BRCA1/2 mutation carriers with primary breast cancer? A systematic review and meta-analysis.Semantic proximity Read ↗

Risk-reducing mastectomy for the prevention of primary breast cancer.Semantic proximity Read ↗

Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations.Semantic proximity Read ↗

Bilateral Prophylactic Nipple-Sparing Mastectomy: Analysis of the Risk-Reducing Effect in BRCA1/2 Mutation Carriers.Semantic proximity Read ↗

Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.Semantic proximity Read ↗

Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer.Semantic proximity Read ↗

Breast cancer after bilateral risk-reducing mastectomy.Semantic proximity Read ↗

Bilateral risk-reducing mastectomy is the safest strategy in BRCA1 carriers.Semantic proximity Read ↗

Risk reduction and survival benefit of prophylactic surgery in BRCA mutation carriers, a systematic review.Semantic proximity Read ↗

Effectiveness of Prophylactic Surgeries in BRCA1 or BRCA2 Mutation Carriers: A Meta-analysis and Systematic Review.Semantic proximity Read ↗

Differences Among a Modern Cohort of BRCA Mutation Carriers Choosing Bilateral Prophylactic Mastectomies Compared to Breast Surveillance.Semantic proximity Read ↗

Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.