Uptake of breast cancer risk-management strategies among unaffected BRCA 1/2 carriers: a systematic review of international evidence.

doi:10.1016/j.ejso.2026.111991

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Article

Uptake of breast cancer risk-management strategies among unaffected BRCA 1/2 carriers: a systematic review of international evidence.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Sept 2026

Godino Lea, Innella Giovanni, Di Palo Chiara, Bono Giuseppe Raffaele, Turchetti Daniela

Abstract excerpt

BACKGROUND: Women carrying BRCA1/BRCA2 pathogenic variants face a substantially increased risk of breast cancer and may choose between risk-reducing mastectomy (RRM) or intensive surveillance. This systematic review aimed to synthesise the available evidence on the uptake of breast cancer risk management strategies among unaffected BRCA1/2 carriers. METHODS: A systematic review was conducted in accordance with...

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Identifiers

PMID: 42442074
DOI: 10.1016/j.ejso.2026.111991

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.