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Article

Risk reducing mastectomy in Norwegian BRCA1/2 carriers.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Mar 2025

Hyldebrandt Hanne Kjensli, Stormorken Astrid Tenden, Vitelli Valeria, Mæhle Lovise, Schlichting Ellen, Grindedal Eli Marie

Abstract excerpt

BACKGROUND: Risk reducing mastectomy (RRM) is an option for women with pathogenic germline variants in BRCA1 or BRCA2 (BRCA1/2). This study investigates and compares RRM-uptake among Norwegian BRCA1/2 carriers from 2008 to 2021, temporal trends, and incidence of breast cancer (BC) after surgery. METHODS: BRCA1/2 carriers without prior breast or ovarian cancer, tested at Oslo University Hospital between January...

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Identifiers

PMID: 39765192
DOI: 10.1016/j.ejso.2024.109571

Genes

BRCA1
BRCA2

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