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Article

Long-Distance Effects of H-NS Binding in the Control of hilD Expression in the Salmonella SPI1 Locus

23 Aug 2021

Abstract excerpt

Members of the foodborne pathogen Salmonella rely on a type III secretion system to invade intestinal epithelial cells and initiate infection. This system was acquired through horizontal gene transfer, essentially creating the Salmonella genus. Expression of this critical virulence factor is controlled by a complex regulatory network. The nucleoid protein H-NS is a global repressor of horizontally acquired...

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PMID: 34424033
DOI: 10.1128/jb.00308-21

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