Article

Bacterial chromatin remodeling associated with transcription-induced domains at pathogenicity Islands

2025-03-11

Abstract excerpt

The nucleoid-associated protein H-NS is a bacterial xenogeneic silencer responsible for preventing costly expression of genes acquired through horizontal gene transfer. H-NS silences several Salmonella Pathogenicity Islands (SPIs) essential for host infection. The stochastic expression of SPI-1 is required for invasion of host epithelial cells but complicates investigation of factors involved in SPI-1 chromatin s...

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Literature Corpus work: 0d07a1c0-ed94-56d7-ad59-6bd4ae611496
DOI: 10.1101/2025.03.11.642640

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