Article

Molecular Basis for the Adaptive Evolution of Environment Sensing by H-NS Proteins

2020-04-24

Abstract excerpt

The DNA-binding protein H-NS is a pleiotropic gene regulator in gram-negative bacteria. Through its capacity to sense temperature and other environmental factors, H-NS allows pathogens like Salmonella to adapt their gene expression, and hence toxicity and biological responses, to their presence inside or outside warm-blooded hosts. To investigate how this sensing mechanism may have evolved to fit different bacteri...

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Literature Corpus work: 6efb0c3f-4c5c-56e7-a779-fb35688bcaf2
DOI: 10.1101/2020.04.21.053520

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