Article
Expression and mutational analysis of the nucleoid-associated protein H-NS of Salmonella typhimurium.
Molecular microbiology - 1 Aug 1992
Hinton J C, Santos D S, Seirafi A, Hulton C S, Pavitt G D, Higgins C F
Abstract excerpt
The H-NS (H1) protein is a major component of bacterial chromatin. Mutations in the hns (osmZ) gene encoding H-NS are highly pleiotropic, affecting the expression of many unrelated genes in an allele-specific manner. H-NS expression was found not to vary with growth phase or growth medium osmolarity. Additionally, 10 independent hns mutations were isolated and characterized. Five of these mutations were the...
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