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Pervasive transcription enhances the accessibility of H-NS-silenced promoters and generates bistability in <i>Salmonella</i> virulence gene expression

2022-04-26

Abstract excerpt

<h4>Summary</h4> In Escherichia coli and Salmonella , many genes silenced by the nucleoid structuring protein H-NS are activated upon inhibiting Rho-dependent transcription termination. This response is poorly understood and difficult to reconcile with the view that H-NS acts mainly by blocking transcription initiation. Here we have analysed the basis for the upregulation of H-NS-silenced Salmonella Pathogenic...

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Literature Corpus work
78b8d059-4cc3-5e0f-b523-1929084eb105
DOI
10.1101/2022.04.26.489344
Open publication

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Pervasive transcription enhances the accessibility of H-NS-silenced promoters and generates bistability in <i>Salmonella</i> virulence gene expressionDOI 10.1101/2022.04.26.489344
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