Article
RNA-binding protein Hfq downregulates locus of enterocyte effacement-encoded regulators independent of small regulatory RNA in enterohemorrhagic Escherichia coli.
Molecular microbiology - 1 Jan 2022
Sudo Naoki, Lee Kenichi, Sekine Yasuhiko, Ohnishi Makoto, Iyoda Sunao
Abstract excerpt
Enterohemorrhagic Escherichia coli (EHEC) causes severe human diseases worldwide. The type 3 secretion system and effector proteins are essential for EHEC infection, and are encoded by the locus of enterocyte effacement (LEE). RNA-binding protein Hfq is essential for small regulatory RNA (sRNA)-mediated regulation at a posttranscriptional level and full virulence of many pathogenic bacteria. Although two early...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.