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Article

Hfq affects the expression of the LEE pathogenicity island in enterohaemorrhagic <i>Escherichia coli</i>

29 Jun 2009

Abstract excerpt

Colonization of the intestinal epithelium by enterohaemorrhagic Escherichia coli (EHEC) is characterized by an attaching and effacing (A/E) histopathology. The locus of enterocyte effacement (LEE) pathogenicity island encodes many genes required for the A/E phenotype including the global regulator of EHEC virulence gene expression, Ler. The LEE is subject to a complex regulatory network primarily targeting ler...

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PMID: 19570135
DOI: 10.1111/j.1365-2958.2009.06781.x

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