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The phosphate-induced small RNA EsrL promotes E. coli virulence, biofilm formation, and intestinal colonization

10 Jan 2023

Abstract excerpt

Escherichia coli are part of the normal intestinal microbiome, but some enterohemorrhagic E. coli (EHEC) and enteropathogenic E. coli (EPEC) strains can cause potentially life-threatening gastroenteritis. Virulence factors underlying the ability of EHEC and EPEC to cause disease include those encoded in the locus of the enterocyte effacement (LEE) pathogenicity island. Here, we demonstrated that EsrL, a small RNA...

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PMID: 36626577
DOI: 10.1126/scisignal.abm0488

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