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Hfq Virulence Regulation in Enterohemorrhagic Escherichia coli O157:H7 Strain 86-24

8 Oct 2011

Abstract excerpt

Enterohemorrhagic Escherichia coli O157:H7 (EHEC) causes bloody diarrhea and hemolytic-uremic syndrome. EHEC encodes the sRNA chaperone Hfq, which is important in posttranscriptional regulation. In EHEC strain EDL933, Hfq acts as a negative regulator of the locus of enterocyte effacement (LEE), which encodes most of the proteins involved in type III secretion and attaching and effacing (AE) lesions. Here, we...

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PMID: 21984790
DOI: 10.1128/jb.06141-11

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