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A Positive Regulatory Loop Controls Expression of the Locus of Enterocyte Effacement-Encoded Regulators Ler and GrlA

16 Nov 2005

Abstract excerpt

The formation of attaching and effacing (A/E) lesions on intestinal epithelial cells is an essential step in the pathogenesis of human enteropathogenic and enterohemorrhagic Escherichia coli and of the mouse pathogen Citrobacter rodentium. The genes required for the development of the A/E phenotype are located within a pathogenicity island known as the locus of enterocyte effacement (LEE). The LEE-encoded...

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PMID: 16291665
DOI: 10.1128/jb.187.23.7918-7930.2005

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A Positive Regulatory Loop Controls Expression of the Locus of Enterocyte Effacement-Encoded Regulators Ler and GrlAPMID 16291665Read ↗

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The Locus of Enterocyte Effacement (LEE)-Encoded Regulator Controls Expression of Both LEE- and Non-LEE-Encoded Virulence Factors in Enteropathogenic and Enterohemorrhagic <i>Escherichia coli</i>Semantic proximity Read ↗

Control freaks—signals and cues governing the regulation of virulence in attaching and effacing pathogensSemantic proximity Read ↗

Coordinate control of the locus of enterocyte effacement and enterohemolysin genes by multiple common virulence regulators in enterohemorrhagic Escherichia coli.Semantic proximity Read ↗

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H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.Semantic proximity Read ↗

Locus of Enterocyte Effacement from <i>Citrobacter rodentium</i> : Sequence Analysis and Evidence for Horizontal Transfer among Attaching and Effacing PathogensSemantic proximity Read ↗

Highly-conserved regulatory activity of the ANR family in the virulence of diarrheagenic bacteria through interaction with master and global regulatorsSemantic proximity Read ↗

Environment Controls LEE Regulation in Enteropathogenic Escherichia coliSemantic proximity Read ↗

Activation of enteropathogenic <i>Escherichia coli</i> (EPEC) <i>LEE2</i> and <i>LEE3</i> operons by LerSemantic proximity Read ↗

The Per regulon of enteropathogenic <i>Escherichia coli</i> : identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)‐encoded regulator (Ler)Semantic proximity Read ↗

Highly-conserved regulatory activity of the ANR family in the virulence of diarrheagenic bacteria through interaction with Master and Global regulatorsSemantic proximity Read ↗

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