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Article

Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile.

Journal of bacteriology - 1 Sept 2014

Boudry P, Gracia C, Monot M, Caillet J, Saujet L, Hajnsdorf E, Dupuy B, Martin-Verstraete I, Soutourina O

Abstract excerpt

Clostridium difficile is an emergent human pathogen and the most common cause of nosocomial diarrhea. Our recent data strongly suggest the importance of RNA-based mechanisms for the control of gene expression in C. difficile. In an effort to understand the function of the RNA chaperone protein Hfq, we constructed and characterized an Hfq-depleted strain in C. difficile. Hfq depletion led to a growth defect,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24982306
DOI: 10.1128/JB.01923-14
PMCID: PMC4135688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile.PMID 24982306Read ↗

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