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Hfq negatively regulates type III secretion in EHEC and several other pathogens

24 Aug 2009

Abstract excerpt

Hfq is a conserved RNA-binding protein that regulates diverse cellular processes through post-transcriptional control of gene expression, often by functioning as a chaperone for regulatory sRNAs. Here, we explored the role of Hfq in enterohaemorrhagic Escherichia coli (EHEC), a group of non-invasive intestinal pathogens. EHEC virulence is dependent on a Type III secretion system encoded in the LEE pathogenicity...

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PMID: 19703108
DOI: 10.1111/j.1365-2958.2009.06856.x

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