Article
Predictive Value of Genetic Risk Scores in the Development of Colorectal Adenomas.
Digestive diseases and sciences - 1 Aug 2022
Gargallo-Puyuelo Carla J, Aznar-Gimeno Rocío, Carrera-Lasfuentes Patricia, Lanas Ángel, Ferrández Ángel, Quintero Enrique, Carrillo Marta, Alonso-Abreu Inmaculada, Esteban Luis M, de la Vega Rodrigálvarez-Chamarro María, Del Hoyo-Alonso Rafael, García-González María Asunción
Abstract excerpt
INTRODUCTION: Unlike colorectal cancer (CRC), few studies have explored the predictive value of genetic risk scores (GRS) in the development of colorectal adenomas (CRA), either alone or in combination with other demographic and clinical factors. METHODS: In this study, genomic DNA from 613 Spanish Caucasian patients with CRA and 829 polyp-free individuals was genotyped for 88 single-nucleotide polymorphisms...
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