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Combinations of single nucleotide polymorphisms identified in genome‐wide association studies determine risk for colorectal cancer

12 Mar 2019

Abstract excerpt

Genome-wide association studies (GWASs) have identified single nucleotide polymorphisms (SNPs) associated with colorectal cancer (CRC) risk, but whether these SNPs have additive effects on the risk of CRC remains unclear. We performed a systematic analysis of GWAS-identified SNPs using GWAS datasets from China (2,248 patients and 3,173 controls) and Europe (4,461 patients and 4,140 controls). We analyzed 58...

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PMID: 30859566
DOI: 10.1002/ijc.32267

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