Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study.

doi:10.1038/srep43263

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Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study.

Scientific reports - 24 Feb 2017

Ibáñez-Sanz Gemma, Díez-Villanueva Anna, Alonso M Henar, Rodríguez-Moranta Francisco, Pérez-Gómez Beatriz, Bustamante Mariona, Martin Vicente, Llorca Javier, Amiano Pilar, Ardanaz Eva, Tardón Adonina, Jiménez-Moleón Jose J, Peiró Rosana, Alguacil Juan, Navarro Carmen, Guinó Elisabet, Binefa Gemma, Fernández-Navarro Pablo, Espinosa Anna, Dávila-Batista Verónica, Molina Antonio José, Palazuelos Camilo, Castaño-Vinyals Gemma, Aragonés Nuria, Kogevinas Manolis, Pollán Marina, Moreno Victor

Abstract excerpt

Colorectal cancer (CRC) screening of the average risk population is only indicated according to age. We aim to elaborate a model to stratify the risk of CRC by incorporating environmental data and single nucleotide polymorphisms (SNP). The MCC-Spain case-control study included 1336 CRC cases and 2744 controls. Subjects were interviewed on lifestyle factors, family and medical history. Twenty-one CRC...

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PMID: 28233817
DOI: 10.1038/srep43263
PMCID: PMC5324108

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