A model to determine colorectal cancer risk using common genetic susceptibility loci.

doi:10.1053/j.gastro.2015.02.010

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A model to determine colorectal cancer risk using common genetic susceptibility loci.

Gastroenterology - 1 Jun 2015

Hsu Li, Jeon Jihyoun, Brenner Hermann, Gruber Stephen B, Schoen Robert E, Berndt Sonja I, Chan Andrew T, Chang-Claude Jenny, Du Mengmeng, Gong Jian, Harrison Tabitha A, Hayes Richard B, Hoffmeister Michael, Hutter Carolyn M, Lin Yi, Nishihara Reiko, Ogino Shuji, Prentice Ross L, Schumacher Fredrick R, Seminara Daniela, Slattery Martha L, Thomas Duncan C, Thornquist Mark, Newcomb Polly A, Potter John D, Zheng Yingye, White Emily, Peters Ulrike

Abstract excerpt

BACKGROUND & AIMS: Risk for colorectal cancer (CRC) can be greatly reduced through screening. To aid in the development of screening strategies, we refined models designed to determine risk of CRC by incorporating information from common genetic susceptibility loci. METHODS: By using data collected from more than 12,000 participants in 6 studies performed from 1990 through 2011 in the United States and Germany,...

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Identifiers

PMID: 25683114
DOI: 10.1053/j.gastro.2015.02.010
PMCID: PMC4446193

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